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REVIEW ARTICLE
Year : 2022  |  Volume : 9  |  Issue : 1  |  Page : 14-17

Anticaries vaccine


1 Assistant Professor, Department of Conservative and Endodontics, Government College of Dentistry, Indore, India
2 Assistant Professor, Department of Periodontia, Government College of Dentistry, Indore, India
3 Reader, Department of Conservative Dentistry and Endodontics, RKDF Dental College and Research Centre, Bhopal, India
4 Professor, Department of Conservative Dentistry and Endodontics, Index Institute of Dental Sciences, Indore, India
5 Tutor, Department of Conservative and Endodontics, Government College of Dentistry, Indore, India
6 Private Practioner, Surat, India

Correspondence Address:
Dr. Neelam Vijaywargiya
Department of Conservative and Endodontics, Government College of Dentistry, Indore, Madhya Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijpcdr.ijpcdr_3_22

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The mutans streptococci bacteria have long been acknowledged as the prime disease-instigating agents in dental caries, the disease that causes tooth decay. Caries vaccines have shown promising outcomes in animal trials, but they are still far from being effective in humans owing to political, monetary, as well as ethical concerns. Candidate vaccines must be evaluated in clinical trials to progress toward practical vaccine development. Passive immunization strategies that appear to be promising will need to be tested further in the clinic.


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